To kill cancer cells using Kanzius RF Therapy, cancer cells are first tagged with tiny objects known as nanoparticles, such as SWNTs and GNPs. When the RF (radio frequency) transceiver apparatus exposes the nanoparticles to the radio frequency signal they heat up, destroying the cancer cells, but don't damage healthy cells nearby.

As of 2007-04-23, preliminary research using the Kanzius RF device at the M. D. Anderson Cancer Center in Houston (by Dr. Steven A. Curley, Professor in Surgical Oncology) and The University of Pittsburgh Medical Center (by Dr. David A. Geller, co-director of the Liver Cancer Center) has shown promising results. If federal approval is granted, testing on human patients would be the next step.